The researchers for six-year studied 4,000 participants with major depressive for an extensive range of symptoms of depression like sadness, suicidal thoughts. These symptoms also included changes in the pattern of sleeping, appetite or weight, concentration, outlook and energy or fatigue.
The researchers studied these parameters at the beginning and at the end of the antidepressant treatment course. During the study, all most all participants reported about three to thirteen residual depressive symptoms while 75% of participants reported five or more symptoms. Whereas 70% reported mid-nocturnal insomnia, 71 % sadness and 70% reported of decreased concentration and decision making. Thoughts of suicide also emerged during treatment.
Madhukar Trivedi, the co-author of the study said that the finding of the study suggests that the use of measurement-based care techniques to identify and target residual depressive symptoms is essential to help patients return to normal function and recover from depression in the long term.